Cerebral blood flow

Cerebral blood flow

class erwin.cbf.ASLBOLDToASL(source, repetition_time, target, cutoff_frequency=0.1125)

Separate ASL signal from ASL-BOLD based on Fourier analysis.

References:

  • Mapping resting-state functional connectivity using perfusion MRI. Chuang et al. NeuroImage 40(4). 2008.

  • Brain perfusion in dementia with Lewy bodies and Alzheimer’s disease: an arterial spin labeling MRI study on prodromal and mild dementia stages. Roquet et al. Alzheimer’s Research & Therapy 8(1). 2016.

Parameters

  • source – Path to source ASL-BOLD image

  • repetition_time – Repetition time (s)

  • target – Path to target ASL image

  • cutoff_frequency – Cut-off frequency between ASL and BOLD (Hz)

class erwin.cbf.pASL(source, echo_time, inversion_times, slice_time, target)

Compute the CBF based on a pASL from Siemens.

References:

  • Comparison of quantitative perfusion imaging using arterial spin labeling at 1.5 and 4.0 Tesla. Wang et al. Magnetic Resonance in Medicine 42(28). 2002.

  • Correcting for the echo-time effect after measuring the cerebral blood flow by arterial spin labeling. Foucher et al. Journal of Magnetic Resonance Imaging 34(4). 2011.

Parameters

  • source – Source ASL image

  • echo_time – Echo time (s)

  • inversion_times – Inversion times (s)

  • slice_time – Path to the slice time image, in the same frame as source

  • target – Target CBF image (mL / 100 g / min)